Wednesday, May 24, 2006
Omega-3 fatty acids reduce mortality risk more effectively than statin drugs
A review published in the April 11 2005 issue of Archives of Internal Medicine analyzed the effects of various lipid lowering regimens on overall mortality and mortality from coronary heart disease. Researchers reviewed 97 clinical trials that included 137,140 men and women receiving treatment and 138,976 control subjects. This analysis compared the mortality risk associated with diet, lipid lowering drugs, omega-3 fatty acids (commonly found in fish oils) and niacin. Statins (a class of lipid lowering drugs) and omega-3 fatty acids significantly lowered both overall and coronary heart disease mortality risk during the trial periods. When compared to controls, overall mortality risk was reduced 13 percent by statin drugs and 23 percent by omega-3 fatty acids. When the risk of mortality from heart disease alone was examined, the use of statin drugs and omega-3 fatty acids were found to lower the risk by 22 and 32 percent, respectively. Since omega-3 fatty acids did not reduce cholesterol levels significantly, researchers suggest that protection against heart arrhythmias, in addition to its anti-inflammatory properties may be responsible for the reduction in mortality risk.
As I watch TV, the airwaves seem to be filled with advertisements for drugs like Lipitor, Crestor, Pravachol, Zocor or Mevacor. These are a class of drugs that are intended to lower the bad (LDL) cholesterol in our blood. The theory being that high cholesterol causes heart disease and heart attacks. Drug ads are really funny. They show a beautiful young couple skipping through a field of flowers without a care in the world. The implication is that by taking their drug, you could look like this too. So . . . You go to your doctor and ask him if "xyz" drug would be good for you. What is he supposed to say? No? So of course he gives you the prescription you ask for and you are off to skip in the flowers. After all, he does not want to lose you as a patient. And we all lived happily ever after. Click here to access a very amusing (but serious) video concerning drug safety.
Baycol (cerivastatin) was marketed a few years ago as a "super-statin." They claimed that it was able to lower LDL cholesterol more than any other drug. Unfortunately, there were not enough human tests done on the drug and many people were severely injured and/or died. It was removed from the market in 2001. The newest statin, Crestor (rosuvastatin) has been marketed as a "super-statin" because AstraZeneca claims it reduces LDL cholesterol to a greater degree than the other approved statin drugs. Like Baycol, Crestor has a number of disturbing side effects:
- Abdominal Pain
- Kidney Failure/Dialysis
Other statin drugs have a similar list of side effects. If you take a statin drug, you should contact your doctor immediately if you experience unexplained muscle pain, tenderness, or weakness, especially if accompanied by a fever or flulike symptoms or yellowing of the skin or eyes, abdominal pain, unexplained fatigue, dark colored urine or pale colored stools. These may be early symptoms of muscle or liver problems from taking a statin drug.
One of the most disturbing side effects (besides death) is muscle pain and weakness, a condition called rhabdomyolysis, most likely due to the depletion of Co-Q10, a nutrient that supports muscle function. Dr. Beatrice Golomb of San Diego, California is currently conducting a series of studies on statin side effects. The industry insists that only 2-3 percent of patients get muscle aches and cramps but in one study, Golomb found that 98 percent of patients taking Lipitor and one-third of the patients taking Mevachor (a lower-dose statin) suffered from muscle problems.
The test for muscle wasting or rhabdomyolysis is elevated levels of a chemical called creatine kinase (CK). But many people experience pain and fatigue even though they have normal CK levels.
Tahoe City resident Doug Peterson developed slurred speech, balance problems and severe fatigue after three years on Lipitor. For two and a half years, he had no side effects at all. It began with restless sleep patterns, twitching and flailing his arms. Loss of balance followed and the beginning of what Doug calls the "statin shuffle"Âa slow, wobbly walk across the room. Fine motor skills suffered next. It took him five minutes to write four words, much of which was illegible. Cognitive function also declined. It was hard to convince his doctors that Lipitor could be the culprit, but when he finally stopped taking it, his coordination and memory improved.
John Altrocchi took Mevacor for three years without side effects; then he developed calf pain so severe he could hardly walk. He also experienced episodes of temporary memory loss.
For some, however, muscle problems show up shortly after treatment begins. Ed Ontiveros began having muscle problems within 30 days of taking Lipitor. He fell in the bathroom and had trouble getting up. The weakness subsided when he went off Lipitor.
In another case, reported in the medical journal Heart, a patient developed rhabdomyolysis after a single dose of a statin. Heel pain from plantar fascitis (heel spurs) is another common complaint among those taking statin drugs. One correspondent reported the onset of pain in the feet shortly after beginning statin treatment. She had visited an evangelist, requesting that he pray for her sore feet. He enquired whether she was taking Lipitor. When she said yes, he told her that his feet had also hurt when he took Lipitor. treatment.
Active people are much more likely to develop problems from statin use than those who are sedentary. In a study carried out in Austria, only six out of 22 athletes with familial hypercholesterolemia were able to endure statin treatment. The others discontinued treatment because of muscle pain.
By the way, other cholesterol-lowering agents besides statin drugs can cause joint pain and muscle weakness.
A report in Southern Medical Journal described muscle pains and weakness in a man who took Chinese red rice, an herbal preparation that lowers cholesterol. Anyone suffering from myopathy, fibromyalgia, coordination problems and fatigue needs to look at low cholesterol plus Co-Q10 deficiency as a possible cause.
So what is rhabdomyolysis any way? It is the breakdown of muscle fibers resulting in the release of muscle fiber contents into the blood circulation, which can be toxic to the kidneys and can result in myoglobinuria and kidney damage.
Myoglobin is a damaging oxygen-binding protein pigment found in the skeletal muscle. When the skeletal muscle is damaged, myoglobin is released into the bloodstream. It is filtered out of the bloodstream by the kidneys. Myoglobin breaks down into potentially toxic compounds causing kidney failure.
Here are a few questions to consider.
- If statin drugs cause the breakdown of muscle fiber (including the heart muscle) and a depletion of Coenzyme Q-10 (a nutrient that supports muscle function), could they actually CAUSE you to have a heart attack?
- If the liver is responsible for regulating up to 80% of my cholesterol levels, why would I want to take statin drugs for lowering cholesterol considering that the number one known side effect of statin drugs is liver damage?
- If cholesterol is the main culprit in heart disease, why don't veins ever get narrowed and blocked?
- If high cholesterol foods are responsible for raising cholesterol levels, then why do people on the high-cholesterol Atkins Diet experience such a significant drop in cholesterol levels?
- Why do Eskimos who eat a traditional diet of almost pure saturated fat (whale and seal blubber) have almost a zero incidence of heart disease?
Dr. Mike Gordon puts it this way:
If a person were healthy, would he/she need drugs to maintain this health? Did nature/God make bodies that were short on chemicals and long on organs? You certainly get this impression from the advertising and most MD's. I submit that the real issue is unhealthy daily habits that are allowed to continue by default when you take drugs to suppress the symptoms of this unhealth. Medicine was intended to be short term, if at all, until you were able to raise your level of health to no longer "need" the drug. Profits have since intervened. We are now told or it is implied that this or that drug is necessary for the rest of our life. This goes against all logic. What other live thing on the planet requires drugs to survive? This argument is made all the more obvious when you see the information I have included below. I would like to offer a few more stats for everyone to consider: "Total number of deaths caused by conventional medicine is an astounding 783,936 per year. It is now evident that the American medical system is the leading cause of death and injury in the US. (By contrast, the number of deaths attributable to heart disease in 2001 was 699,697, while the number of deaths attributable to cancer was 553,251" These stats are from Life Extension Magazine March 04. Article DEATH BY MEDICINE You and I are responsible for being healthy. It comes from healthy choices each day, not in a bottle. Dr. Mike Gordon
Check out some surprising information about Statin drugs:
Physicians have for the most part been very discouraged with the results of First-Step Therapy and have a tendency to simply write a prescription without offering their patients an opportunity to improve their clinical situation with healthy lifestyle changes. This is happening because physicians believe that their patients will simply not be able to make these lifestyle changes or even if they do, they will not be that effective. This attitude along with the tremendous amount of marketing by the pharmaceutical industry directly to the patient has led individuals to believe that their best option is to just begin taking medication. However, it is becoming more evident each and every day that there is also an inherit risk with taking any medication. In fact, adverse drug reactions to properly prescribed and properly administered medication are the FOURTH leading cause of death in this country.
Talk to your physician about the side effects of statin drugs which might include:
Inability to concentrate
Lowered sex drive
Weakened immune system
Shortness of breath
Rhabdomyolysis (painful bursting of muscle cells)
Explain your concern about these kinds of side effects and educate yourself about the Cholesterol Myth. Click on (and read) my post on the Cholesterol Conspiracy to learn why statin drugs are not the best answer for dealing with heart disease.
Cholesterol MythCholesterol Conspiracy
The Healthy for Life Program is an effective, internet based lifestyle program that has been shown in clinical trials to significantly lower your cholesterol, lower your blood pressure, prevent diabetes, reverse pre-clinical diabetes, and decrease your risk of heart disease. What is even more exciting is the fact that there was also a significant weight loss in those participants that needed to lose weight. That's right. These are healthy lifestyles that simply have a side effect of permanent weight loss. Participants from all over the country are joining the Healthy for Life Program as a way to protect their health or even regain their health as they decrease their dependence on medication and begin releasing fat. I encourage you to take a closer look at this exciting new program by clicking on to the link below:
Healthy For Life Program
In a 12 week clinical study, people on the Healthy For Life program significantly lowered their cholesterol. Total cholesterol dropped from an average of 206 mg/dL (Baseline) to 176 mg/dL (Final). Most of this decline resulted from a drop in LDL cholesterol from an average of 134 mg/dL (Baseline) to 111 mg/dL (Final).
Pass this by your doctor as an alternative to cholesterol lowering drugs and have him monitor the results. I'm sure you will both be pleased with the outcome.
P.S. No nasty side effects